Search results for "Deproteinisation-resistant DNA-protein complexes"

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Tight DNA-protein complexes isolated from barley seedlings are rich in potential guanine quadruplex sequences

2020

Background The concept of chromatin domains attached to the nuclear matrix is being revisited, with nucleus described as a set of topologically associating domains. The significance of the tightly bound to DNA proteins (TBP), a protein group that remains attached to DNA after its deproteinization should be also revisited, as the existence of these interactions is in good agreement with the concept of the topologically associating domain. The work aimed to characterize the DNA component of TBP isolated from barley seedlings. Methods The tight DNA-protein complexes from the first leaves, coleoptiles, and roots of barley seedlings were isolated by purification with chromatography on nitrocell…

Circular dichroismGuaninelcsh:MedicinePlant ScienceGC-rich DNAG-quadruplexDeproteinisation-resistant DNA-protein complexesGeneral Biochemistry Genetics and Molecular Biology03 medical and health scienceschemistry.chemical_compoundBarleyMolecular Biology030304 developmental biology0303 health sciencesOligonucleotideChemistryGeneral Neurosciencelcsh:R030302 biochemistry & molecular biologyStructural geneCell BiologyGenomicsGeneral MedicineNuclear matrixG-quadruplexesChromatinBiochemistryGeneral Agricultural and Biological SciencesDNAPeerJ
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